From: Initiation of antihypertensive monotherapy and incident fractures among Medicare beneficiaries
Drug Class | 1–14 days after initiation | 15–365 days after initiation | ||||||
---|---|---|---|---|---|---|---|---|
# Fractures | P-Yrs | Rate Per 10,000 P-Yrs (95% CI) | SMRW HR (95% CI) | # Fractures | P-Yrs | Rate Per 10,000 P-Yrs (95% CI) | SMRW HR (95% CI) | |
ACE | 54 | 1539 | 351 (266, 454) | ref | 1271 | 36,618 | 347 (328, 367) | ref |
ARB | 14 | 420 | 333 (190, 546) | 0.92 (0.49, 1.75) | 322 | 10,032 | 321 (287, 358) | 0.96 (0.84, 1.09) |
BB | 58 | 1416 | 410 (314, 526) | 1.00 (0.65, 1.54) | 1375 | 33,449 | 411 (390, 433) | 1.09 (1.00, 1.19) |
CCB | 27 | 705 | 383 (258, 550) | 0.82 (0.50, 1.36) | 720 | 16,540 | 435 (404, 468) | 1.11 (1.00, 1.24) |
THZ | 27 | 617 | 438 (294, 628) | 1.40 (0.78, 2.52) | 562 | 14,656 | 384 (353, 416) | 1.02 (0.90, 1.15) |