From: Initiation of antihypertensive monotherapy and incident fractures among Medicare beneficiaries
Drug Class | Probable Low Bone Mineral Density Fractures | Normal Bone Mineral Density Fractures | ||||||
---|---|---|---|---|---|---|---|---|
# Fractures | P-Yrs | Rate Per 10,000 P-Yrs (95% CI) | SMRW HR (95% CI) | # Fractures | P-Yrs | Rate Per 10,000 P-Yrs (95% CI) | SMRW HR (95% CI) | |
ACE | 424 | 38,157 | 111 (101, 122) | ref | 901 | 38,157 | 236 (221, 252) | ref |
ARB | 99 | 10,452 | 95 (77, 115) | 0.93 (0.74, 1.17) | 237 | 10,452 | 227 (199, 257) | 0.97 (0.84, 1.13) |
BB | 464 | 34,864 | 133 (121, 146) | 1.08 (0.93, 1.26) | 969 | 34,864 | 278 (261, 296) | 1.09 (0.98, 1.21) |
CCB | 280 | 17,245 | 162 (144, 182) | 1.13 (0.95, 1.35) | 467 | 17,245 | 271 (274, 296) | 1.09 (0.96, 1.24) |
THZ | 171 | 15,273 | 112 (96, 130) | 0.85 (0.68, 1.06) | 418 | 15,273 | 274 (248, 301) | 1.12 (0.98, 1.29) |