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Table 4 Unadjusted Risk-Related Driving Indicators by Tier 1 Drug Class: Mean (Standard Deviation)

From: Medication use and driving patterns in older drivers: preliminary findings from the LongROAD study

Drug Class (N Taking Drug)Deceleration RateapSpeeding RatebpRight/Left turn Ratiocp
Use of Drug:NoYes NoYes NoYes 
Antihistamine (396)5.4 (6.2)5.7 (7.2).337.6 (16.4)9.27 (21.8).07.93(.13).95(.14).01
Anti-infective (295)5.4 (6.4)5.5 (5.9).767.8 (17.6)8.2 (14.5).73.93(.13).94(.13).89
Anti-neoplastic (111)5.4 (6.3)7.7 (17.1).107.7 (17.1)10.7 (21.1).07.94(.13).95(.14).42
Autonomic drugs (648)5.3 (6.0)6.0 (7.6).017.6 (16.5)8.8 (19.7).12.93(.13).94(.13).41
Blood formulation, coag, thrombosis (389)5.3 (6.3)6.0 (7.0).087.9 (17.7)7.2 (13.9).43.94(.13).94(.15).90
Cardiovascular drugs (2146)5.5 (6.1)5.4 (6.5).698.3 (18.6)7.7 (16.8).43.94(.13).94(.13).80
CNS agents (2051)5.2 (6.3)5.5 (6.4).237.1 (16.0)8.1 (17.8).13.93(.14).94(.13).23
Electrolytic, Caloric and Water Balance (1601)5.8 (7.2)5.1 (5.6)<.018.7 (18.7)7.1 (16.0).01.94(.13).94(.13).86
Respiratory Tract Agents (105)5.4 (6.4)6.0 (6.2).347.6 (17.2)9.8 (20.0).23.94(.13).93(.13).81
Eye Ear Nose and Throat Preparations (718)5.2 (6.1)6.0 (7.1)<.017.9 (17.0)7.7 (18.0).82.93(.13).94(.13).13
Gastrointestinal drugs (944)5.3 (6.4)5.6 (6.4).217.6 (16.4)8.4 (19.0).25.93(.13).94(.13).20
Hormones and Synthetic Substitutes (1300)5.1 (6.0)5.9 (6.8)<.017.4 (16.0)8.4 (18.7).10.93(.13).94(.13).17
Local anesthetics (23)5.4 (6.2)10.0 (17.6)<.017.8 (17.2)11.6 (24.2).30.94(.13).96(.14).47
Skin and Mucous Membranes (484)5.3 (6.1)6.0 (7.6).037.7 (16.9)8.6 (18.8).30.93(.13).94(.13).45
Smooth Muscle Relaxants (89)5.4 (6.4)5.5 (5.1).867.9 (17.4)6.8 (13.9).55.94(.13).94(.13).58
Vitamins (1899)5.6 (6.7)5.4 (6.2).418.3 (18.6)7.6 (16.5).27.94(.13).94(.13).91
Miscellaneous agents (371)5.4 (6.5)5.5 (5.6).857.6 (16.7)9.5 (20.5).05.93(.13).95(.13).10
  1. a Number of high deceleration (≥0.35 g) events events per 1000 miles driven
  2. b Number of speeding (> 80 mph) events per 1000 miles driven
  3. c Ratio of right turns to left turns; a higher mean ratio is indicative of possible reluctance to make left turns against oncoming traffic