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Table 5 Model-based Relationship (B) between Medication Class and Driving Outcomes, Adjusted for Covariatesa

From: Medication use and driving patterns in older drivers: preliminary findings from the LongROAD study

 SpeedingRapid DecelerationRight-to-Left Turn Ratio
Medication ClassBp-valueBp-valueBp-value
Antihistamine−.018.790−.010.779.016.016
Anti-infective agents.059.424−.027.515−.012.096
Anti-neoplastic agents.221.054.058.376.008.469
Autonomic.024.670.052.099.005.394
Blood Formation, Coagulation−.079.242.021.586−.003.674
Cardiovascular−.031.561−.055.068−.004.487
CNS agents.143.004.040.165.040.165
Electrolytic−.078.105−.110<.001.000.933
EENT−.075.164.046.139.003.583
Gastrointestinal drugs.058.242.061.032.006.219
Hormones and synthetic substitutes.054.252.060.024.003.562
Local anesthetics−.002.993.133.350.001.966
Skin and mucous membrane agents−.005.936.029.423−.005.454
Smooth Muscle Relaxants.007.957−.020.779−.002.893
Vitamins−.021.675−.034.228−.010.053
  1. aCovariates: total number of medications, miles driven per year, total days driving, sex, age, race/ethnicity, education, urban/rural residence, income, employment, study site