Risk Factors | ORa (95% CI) | p-value |
---|---|---|
Polysubstance by number of substances | ||
Opioids only | Reference | |
Opioids + 1 substance | 0.94 (0.77–1.15) | 0.58 |
Opioids + ≥ 2 substance | 0.82 (0.67–1.02) | 0.08 |
Polysubstance by types of substances | ||
Opioids only | Reference | |
Opioids and alcohol | 0.79 (0.55–1.16) | 0.24 |
Opioids and stimulants | 1.15 (0.84–1.58) | 0.37 |
Opioids and benzodiazepines | 0.79 (0.59–1.06) | 0.12 |
Opioids, stimulants and benzodiazepines | 0.67 (0.39–1.16) | 0.13 |
Opioids, alcohol and benzodiazepines | 0.48 (0.23–0.98) | 0.04 |